TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.45nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition concentration against isoleucyl tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.67nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.87nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.98nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 14.1nMAssay Description:Compound stocks were prepared at a 10 mM concentration in dimethyl sulfoxide.T. brucei bloodstream forms (100 µl at 2.0 × 10^4 parasites/ml) were pla...More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >54nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 242nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus 11481More data for this Ligand-Target Pair
Affinity DataIC50: 265nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 279nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus 11481More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 494nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.27E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.46E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus C 7More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair